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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dd19fd7dbed80dbf2118e89be57a5cf7c80348a84c371c54ac85df801e312525' 
  AND token = 'LoWTyI6vJxbZtPbyJjuU0gwgZjLlhTj0f5DXPOJEPzw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}