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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9edfbc2d357ca123e79119647b408258f87d7faca5b1dbc73ebb92c29b58f4e3' 
  AND token = 'ppObLs+OBof+vxk/tAYO2uf24bp1eJdlN4yp/PniFU8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}