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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3478180a797231d595e1060162c4ade27d704c4cb3285c56c452864fb8ff5225' 
  AND token = '931xWuD03oH+WHCc6QxJz10aD4yOMWWskrIRqxgPEHU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}