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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4347751e07bb64882d454505db7915e9f1c752fc4e6b1f7c44eede791f87caba' 
  AND token = '+ZQQhIYk7udSf9P913e+yvTKcxoS08FHu2nwWvj/2cg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}