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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '85a6130dec36c5d39945159ec10015950e0e3b3d5a1c91cce7d08e1294f7a2a6' 
  AND token = 'JrZaOK+E5yr2rA0SuPyUm2JU8qaGc/CrHS6QrHlFSds=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}