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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e21d6bee32ba3d86a4dd7d4f83ce6b249bbd0150de998fc8b015e931b564862' 
  AND token = 'B4Nu+niQ4l9Cu4tH7y2U8qK7o/bo4woIz60Hiy/Rtok=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}