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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b0eee301d134bd0e0a15e8d698f50377fc3e0d9828d1c2d7b6de690437a63020' 
  AND token = 'yBN+PredN03xAWsK7BJmUHFgYacWLlEs4sjo5NVpdVg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}