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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '15fed5e065ca1627054dd46b95f4feea53b3dded0d14d1e6da9c6f012a5c91f0' 
  AND token = 'AW2S+c3JbbnyOLw8aH8Qnq//8IbxbrVP5rHMVpwLGyU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}