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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '61a1969ca7617152abdfe19b14b9e78e7abfa1ed9c497b62224f1b3e9ed61199' 
  AND token = 'xyoCrw2oht3h/4pcjV8G9HqMfm7lmHSCyYuaoKqWD9Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}