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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33160de70dad64928b58f4bd15f454312596975cdc018a1069005779ebf3901e' 
  AND token = 'twDT5qy7O7WdyOOdmZ99kMuGHfcyglIt0NmimstwJU0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}