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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e8496fe1b058ed8a38fce111c36ff8375a2edd13e80f63d5eacfbd637f8efc7f' 
  AND token = 'E4NeC00kGqs+rp+l8H1Z2oXWf9DgPPy1wbvM2CoygHc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}