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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9e1c0a9f1b7180a04bdb56be09364180709994b71e01fb612e33d71fd3e19568' 
  AND token = 'ZpUQaZTzleqOcRTFZSGHGf1x0TkdtXk4644EjeCYLro=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}