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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '429332cb65fc5dbd6819e4031c49962a4864cc4d61ca09501eb7136cea430020' 
  AND token = '2sgYzTxCAQ7zkxDiLlBHvxTSWK0tSkx0r57I/7RyWbY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}