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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '800cb59bb0ee96159cd90b86a99db50c9903e9a1c50e9517183a163b18eb4193' 
  AND token = 'Ak9XdPSzT+BRiv2TjgyxUQLNI8Z+eOWNfUycUQio/4A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}