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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '15641399d6adc5a8a4317aecffbef3fc6a5b1dffd8f2be6fe85686dad7bb0efc' 
  AND token = '0ILCowJ1OyHHZKrr5C3X+tD46g71q1BDGsb7NQez10Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}