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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e059dd24d232914d7750497c65f5500aa02a5f396c1b205d4567e0a084e80f7a' 
  AND token = 'DAasx90i8SG2t33sRJR6CgiGmZNkTklVvTQBIx/Ir6o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}