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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6824d964f01dab8638afc6ed5c124d47ad3e12d4893fdfd3a0123ea4012e633a' 
  AND token = 'rPPuXyP2vqUtXCqnBHQQeOwPHiQPnYsjZdIECWtbHCQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00063

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}