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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cd7e33397cc59fd86ed68c5c8c329bbfad3dc2ebee51beb422247a30c291d422' 
  AND token = '7xLBQW1BrjYqHaTqPUe4a+Uh+IfB29zQoknZOnJLu5I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}