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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed02553b56cf51fde9a8306256c9bfc319b4c85165d359557a12f884f1c36bc6' 
  AND token = 'IJxOqoCXcfQ93dz7N7WNfuRISjj95XgvXk5fWASUMCQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}