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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '010488e000906d3e62b4ac663049ab966a7b80a2b6f3ef20e6270975784ac87c' 
  AND token = 'ld7Z++U1TgxMJDGZ6QfpMbMOEHnOzHgqZmAJ9bAgTcI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}