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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '055ca224cb762cb9a83a51f8780fd30e7d7be146f60a4b441aa1d3bb308f848e' 
  AND token = 'LN3d7DuMetYo1QD5qoAxdVyGDM0E1wUVRb3NTirBmlY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}