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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e5d1a0b0900c32e35a0bfab60e5517847c90214de4663b480bf144cb14f7c0c' 
  AND token = 'CvRA/5YhwrZwpaPhFzlzbyN86OphxbJ1HV+4hUwArDs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}