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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd6bede8bc1d1865ddb7d946add3f481778e87a9937a160fc2599b61a7b728bbc' 
  AND token = 'DqFlv+rcvJLIj31Zw9JbJ84D12nCUpZ4b6Q6r1+nqWo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}