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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e41fb76a4f1bfff75bafa5407f3a4eb13e776f541ec9b0db3b793db3ea0b468' 
  AND token = 'qt5kEwoRFY0TDkqivCVt9WsSbJlAqvt48mg1WsSGi9A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}