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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5417ea8df81a45c37a35f6332e157f51b46bef2ce6c221433dfc0ecdb8239701' 
  AND token = 'YDqAUlBtcarpl+/lp3YV+3bz7T/E+qYJ6NUg+sk9s6Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}