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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6cc47668a68c5101406a45d2f88988ed48ac399ba5ca53dae3050c9be05814d0' 
  AND token = 'IYMQG+s27NK0N+lcZVPx5tJevd2UUgF+q5mzZdXh3RI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}