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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b3de60bde9edd9c8a91f5058ac3667acd643356dd2e18b0a85be4c69304e781' 
  AND token = '1B/0iiwbJ1j9mPvvd/z8m4bRfVE/J9IT4oooI+Uznq0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}