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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '44429fcc227ef12cb35777ccb59a98c467f8982e7fb72cceb04514f9fcf83171' 
  AND token = 'TYnim/2etx3TxIw4KQU1VXVZTKSBJLAT4Ss3bLYSb0A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}