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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3253ace16c3189f3a343b0587228afe00976ba59e489625bc6726448087df518' 
  AND token = '8bA0cZ4edcj6pBqt3LVAYxTAN/68FaTZrTxRnrqDQmE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}