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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '662f0d5cdd50fa2a500477e8074b20695f1ba034db8bf7089ea6ebf7771ba609' 
  AND token = 'Xqyk3fbQoM3dKFJUCABY9E7SlzEMC5tjjAWFXMgiwM4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}