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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eefd2a3054160591c755bbcea3e2c3815714247697d80e2c17fdb3c86e3b951b' 
  AND token = 'GdeV6ZAsu0pwaetEGYbLZgO18ijl5CbF6FCsUi93Vb0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}