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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '103a7303951414e755f8eb3efcdafd8665a31ebf485bd4f1bb7a0fec60b5bb86' 
  AND token = 'QsOQzkF8z3WXnioJJuMI5+vcwW4x/hsUkiXK/W+JhMs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}