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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f46a308ef3588a6f2f8edb6dd5f85886baf385d316cc3f616200b3c7c768615d' 
  AND token = 'Ho8VJtU5k9QJjqVV6L9AwMxjyiwA1TkxJbhwcIrHAck=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}