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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '12f2782b28e40c482bc23591fa4996932544239731c72826f131a049fde1a5ed' 
  AND token = 'CAUz7Bk7BXYbcrIR4EaPP7AaIl9HhBILhO6+uhP2cVY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}