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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c74fcad4dc20154edc634eb6c8e56002bc091746b26f3b266d8ffac892143764' 
  AND token = 'eHVV8Ng+jYuG/qg07yHHbsNgzzqQqnfTJwr2k0fHq4I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}