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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e319533453a92909be80d9e8fbc67a2a8bef2a485705349cdd5ee652909f7a01' 
  AND token = 'ebq2eX8HlHggP7HjKh6F9lLbaOBt1Vp0jWmF0lFpNTQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}