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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0d2f4d6b24b2cb0b40e5f1546b121b86eb0d86e309799f426dd341ec4da0e1ad' 
  AND token = '3JmxmG1ZahRnfsAlMvgXUhufNrFXGOEs5GUwRW4LZRk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}