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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '92ed1297d8a2931c91d4698b6d6f76acff08153bcdbc726af7f9872dad1b3676' 
  AND token = 'IbYffNEo3wk8IcxbPzho8xEqYu/Km9tohWhwUvmckws=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}