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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b90e8d5e32f889a4381875673504bc24e1406bbf009cebd13e909b019c466616' 
  AND token = 'a2adRYGXoI0l1fWGxyig+5ekH4pBXSwHd8iBAeltdKA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}