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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '111b5f1ab6e86bb3cdc2703852ba27166417abdd28add77f626c10e4e1288670' 
  AND token = 'nezg+ceNA+DRahN9C7TAFuAoXuLRnivIwJMLE5YuORs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}