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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ca4280372b8e5b713586b90936212cb182d092ade8bb0a9b844d401c991e6959' 
  AND token = 'KG2bbVbAEx6mbvDwpteesx0M/uPj6EiXQx+rrtiRRzQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}