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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '35cc5fce0c205e78b330f08073629fa6834048cdfb05a31cd8ab821fc8e220cb' 
  AND token = '9QQGxKIiA9flEMfeDP9r8DYEeEJs7uG/FG6oBWTQeMQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}