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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2667fa9510fa0c4e6e13e1e8c17521e5ac92966349e64196ddbd79b8a9967721' 
  AND token = '+dxMIj4bOLuxFi6v1MCe+A9zI1JsuBn/dy1nmAqPKcA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}