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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2597e9423285f27d325e51a1f7cbc2383e016e7379b898d5a1aa4a3789dfa753' 
  AND token = '3AeqB6Iwbc4rrP/XwPUIcLkz0md9nKaF7p9DZrs+1QI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}