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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '145cb80f917e77be5c11b5f4e5b8d5d11001fbdce711482e0fa83b875dd3a53b' 
  AND token = '0sSVV+YCfMleQE3KkNgqMXmM1ym0s55HzYZixR34wA0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}