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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c8e1400ead1707c3c76b06882c6d4f07fab94ae5fcfeed0adc9083f5fe5264da' 
  AND token = 'uE/WsuyukLn0dg/bJF5na8zwrKl83HSa+oFjwQUVOrI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}