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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7e206eb00e8fe25468e94b8448aa7ae75757d63ac1ff8cd573a7f06115629816' 
  AND token = '7umA+JIWK81o6n17BDz5ZNDkOWmT3hQCFCbNnzuwUaM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}