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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1436ab3170a9889696f4764791ec8518ce965fc55a909e5e1b209ce78b6cfd9c' 
  AND token = 'SMFiBDqSxjw/jT1KGTgyUtU9iHWDrPZy+JHc5e17+L0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}