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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a3582dde65cc314eb93334c54c130cbd7273ba2a5d92271dcfa7c8f50c794c08' 
  AND token = 'ax8SO8bm2VCzyB9LQodYTr+UZ/B7rd7lrcYvHbjNm5o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}