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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1212f7a0ea347190ffbfbd718922270890042bde2473894e81ec679ec43164de' 
  AND token = '45Fig59JHBWv/UW7yv5XbDeL1DJhsOHWxD81OwFqjeE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}